Estimation of intracranial pressure by ultrasound of the optic nerve sheath in an animal model of intracranial hypertension

Background Ultrasound of the optic nerve sheath diameter (ONSD) has been used as a non-invasive and cost-effective bedside alternative to invasive intracranial pressure (ICP) monitoring. However, ONSD time-lapse behavior in hypertension (ICH) its relief by means either saline infusion or surgery are still unknown. The objective this study was correlate ultrasonography (ONS) an experimental animal model ICH determine interval needed for return baseline levels. Methods An conducted on 30 pigs. evaluated ultrasound at different ICPs generated balloon inflation, infusion, deflation, measured using intraventricular catheter. Results All variables obtained ONS such left, right, average (AON) were statistically significant estimate ICP value. changed immediately after inflation returned delay min deflation (p = 0.016). No statistical significance observed values with hypertonic infusion. In swine model, showed linear correlation could be estimated formula: ?80.5 + 238.2 × AON. Conclusion present study, measure ICP, although short returning levels case sudden relief.